Division of Pharmacoepidemiology at Brigham and Women’s Hospital Named Recipient of $523,204 PCORI Pilot Project to Study Primary Medication Adherence

Project Part of National Effort to Improve Methods for Patient-Centered Outcomes Research

BOSTON, Mass. (June 18, 2012) – The Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women’s Hospital has been selected to receive $523,204 from the Patient-Centered Outcomes Research Institute (PCORI) to develop and test a decision support tool for primary medication adherence, PCORI announced today. The award is part of PCORI’s Pilot Projects Program, which will address a broad range of questions about methods for engaging patients in various aspects of the research and dissemination process.

Jennifer Polinski, ScD, MPH, Instructor in Medicine will lead the two-year research project at Brigham and Women’s Hospital. The project will focus on identifying patient-, physician-, and pharmacist-based factors that affect whether or not patients fill an initial prescription for a new medication, a phenomenon known as primary medication adherence. Based on these findings, a decision support tool to encourage primary adherence will be created and disseminated. The project will focus on primary adherence to antihypertensive medications. The funding for Brigham and Women’s Hospital has been approved pending completion of a business review and a formal award agreement with PCORI.

PCORI is an independent, non-profit organization whose establishment was authorized by Congress in 2010. Its mission is to fund research that will provide patients, their caregivers and clinicians with the evidence-based information needed to make better-informed health care decisions.

“The Pilot Projects will improve our understanding of how to conduct research and disseminate research findings in ways that are more responsive to the needs of patients and the health care community,” said PCORI Executive Director Joe Selby, MD, MPH. “We are excited to be funding 50 projects nationwide, led by creative and innovative researchers. Their work will help us establish a foundation for patient-centered outcomes research that will give patients, caregivers and clinicians the tools they need every day.”

PCORI is committing $30 million in funding over two years for the pilot projects, which were selected by PCORI ‘s Board of Governors through a competitive, multi-stage review process. Proposals were evaluated for their scientific merit and rigor and fit within eight areas of interest outlined in the pilot projects announcement.

Awards, approved for research institutions in 24 states and the District of Columbia, include those for projects designed to develop a range of tools and techniques aimed at improving patient-centered care and decision-making; create new patient-centered care measures; and improve delivery of patient-centered counseling and care in various health care settings.

“We know that approximately 28% of prescriptions for a newly prescribed drug are not filled,” said Jennifer Polinski, ScD, MPH, Principal Investigator of the study. “We hope that by developing a decision support tool to aid patients and their providers in a shared discussion about factors that influence primary adherence, we can improve the likelihood that patients fill new prescriptions.”

For more information about the PCORI Pilot Projects, visit www.pcori.org.

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About PCORI
The Patient-Centered Outcomes Research Institute (PCORI) is an independent, non-profit organization authorized by Congress. Its mission is to fund research that will provide patients, their caregivers and clinicians with the evidence-based information needed to make better-informed health care decisions. PCORI is committed to continuously seeking input from a broad range of stakeholders to guide its work. More information is available at www.pcori.org.

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