Elisabetta Patorno, MD, DrPH

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Brigham & Women’s Hospital
Department of Medicine
Division of Pharmacoepidemiology & Pharmacoeconomics
1620 Tremont Street, Suite 3030,
Boston, MA 02120

epatorno@partners.org
Phone: 617-278-0930 | Fax: 617-232-8602


Elisabetta Patorno, MD, DrPH, is an Assistant Professor of Medicine at Harvard Medical School and an Associate Epidemiologist in the Division of Pharmacoepidemiology and Pharmacoeconomics at the Brigham and Women’s Hospital. Her research focuses on the assessment of the safety and effectiveness of therapeutics through the application of advanced epidemiologic and statistical methods for confounding adjustment in non-interventional studies. Her major clinical areas of interest include the pharmacoepidemiology of diabetes, neurological diseases, and the assessment of therapeutics and procedures in the setting of acute hospital care. She has also particular interest in the advancement of methods to improve causal inference in pharmacoepidemiological studies using large health care utilization databases, with a particular emphasis on study design and propensity score methodology for confounding adjustment. She currently serves as Chair-elect of the Comparative Effectiveness Research Special Interest Group of the International Society of Pharmacoepidemiology and Therapeutic Risk Management.

Dr. Patorno graduated magna cum laude with a Doctor of Medicine degree from the University of Modena and Reggio Emilia (Italy), where she also completed her training in Preventive Medicine. She earned a Master degree in Public Health and a doctorate in Pharmacoepidemiology at Harvard School of Public Health.

Selected Publications | Current PubMed Search Results

  • Patorno E, Goldfine AB, Schneeweiss S, Glynn RJ, Liu J, Kim SC. Cardiovascular Outcomes among Initiators of Canagliflozin versus Other Non-Gliflozin Antidiabetic Agents: a Population-based Cohort Study. BMJ 2018;360:k119
  • Patorno E, Gopalakrishnan C, Franklin JM, Brodovicz KG, Masso-Gonzalez E, Bartels DB, Liu J, Schneeweiss S. Claims-based studies of oral glucose-lowering medications can achieve balance in critical clinical variables only observed in electronic health records. Diabetes Obes Metab. Epub 2017 Dec 5
  • Hernandez-Diaz S, Huybrechts KF, Desai RJ, Cohen JM, Mogun H, Pennell PB, Bateman BT, Patorno E. Topiramate use early in pregnancy and the risk of oral clefts: A pregnancy cohort study. Neurology. 2018;90(4):e342-e351
  • Huybrechts KF, Bateman BT, Desai RJ, Hernandez-Diaz S, Rough K, Mogun H, Kerzner LS, Davis JM, Stover M, Bartels D, Cottral J, Patorno E. Risk of neonatal drug withdrawal after intrauterine co-exposure to opioids and psychotropic medications: cohort study. BMJ. 2017;358:j3326
  • Patorno E, Glynn RJ, Levin R, Lee MP, Huybrechts KF. Benzodiazepines and risk of all cause mortality in adults: cohort study. BMJ. 2017;358:j2941
  • Fralick M, Schneeweiss S, Patorno E. Risk of Diabetic Ketoacidosis after Initiation of an SGLT2 inhibitor. N Engl J Med. 2017;376(23):2300-2302
  • Patorno E, Huybrechts KF, Bateman BT, Cohen JM, Desai RJ, Mogun H, Cohen LS, Hernandez-Diaz S. Lithium Use in Pregnancy and the Risk of Cardiac Malformations. N Engl J Med. 2017;376(23):2245-2254
  • Patorno E, Bateman BT, Huybrechts KF, MacDonald SC, Cohen JM, Desai RJ, Panchaud A, Mogun H, Pennell PB, Hernandez-Diaz S. Pregabalin Use Early in Pregnancy and the Risk of Major Congenital Malformations. Neurology. 2017;88(21):2020-2025
  • Patorno E, Everett BM, Goldfine AB, Glynn RJ, Liu J, Gopalakrishnan C, Kim SC. Comparative Cardiovascular Safety of Glucagon-Like Peptide-1 Receptor Agonists versus Other Antidiabetic Drugs in Routine Care: a Cohort Study. Diabetes, Obesity and Metabolism. 2016;18(8):755-65
  • Kumamaru KK, Kumamaru H, Bateman BT, Gronsbell J, Cai T, Liu J, Higgins LD, Aoki S, Ohtomo K, Rybicki FJ, Patorno E. Limited Hospital Variation in the Utilization and Yield of CT for Pulmonary Embolism in Patients Undergoing Total Hip or Knee Replacement Surgery. Radiology. 2016;281(3):826-834
  • Patorno E, Wang SV, Schneeweiss S, Liu J, Bateman BT. Patterns of beta-blocker initiation in patients undergoing intermediate to high risk non-cardiac surgery. American Heart Journal. 2015;170(4):812-820.e6
  • Patorno E, Patrick AR, Garry EM, Schneeweiss S, Gillet VG, Bartels DB, Masso-Gonzalez E, Seeger JD. Observational studies of the association between glucose-lowering medications and cardiovascular outcomes: addressing methodological limitations. In press Diabetologia 2014.
  • Patorno E, Neuman MD, Schneeweiss S, Mogun H, Bateman BT. Comparative safety of anesthetic type for hip fracture surgery in adults: retrospective cohort study. BMJ. 2014;348:g4022.
  • Patorno E, Glynn, RJ, Hernandez-Diaz S, Liu J, Schneeweiss S. Studies with many covariates and few outcomes selecting covariates and implementing propensity-score–based confounding adjustments. Epidemiology. 2014;25(2):268-78.
  • Patorno E, Glynn, RJ, Hernandez-Diaz S, Avorn J, Wahl PM, Bohn RL, Mines D, Liu J, Schneeweiss S. Risk of ischemic coronary and cerebrovascular events in adult users of anticonvulsant medications in routine care settings. J Am Heart Assoc. 2013;2(4):e000208.
  • Patorno E, Grotta A, Bellocco R, Schneeweiss S. Propensity Score Methodology for Confounding Control in Health Care Utilization Databases. EBPH. 2013;e8940-1- e8940-16.
  • Patorno E, Bohn RL, Wahl PM, Avorn J, Patrick AR, Liu J, Schneeweiss S. Anticonvulsant Medications and the Risk of Suicide, Attempted Suicide, or Violent Death. JAMA. 2010;303(14):1401-1409.
  • Polito A, Patorno E, Costello JM, Salvin JW, Emani SM, Rajagopal S, Laussen PC, Thiagarajan RR. Perioperative factors associated with prolonged mechanical ventilation after complex congenital heart surgery. Pediatr Crit Care Med. 2011;12(3):e122-6.